Multisystem neuronal involvement and sicca complex: broadening the spectrum of complications

We report two patients with multisystem neuronal involvement associated wit h sicca complex. One had a lower motor neuron syndrome combined with a flac cid bladder and rectum. The second patient had unilateral hearing loss, sen sory neuronopathy, Adie's pupils, upper motor neuron signs, and autopsy-pro ven anterior horn cell degeneration. Our cases lead us to propose that the spectrum of neuronal involvement occurring with sicca syndrome may be wider than is currently appreciated. (C) 1999 John Wiley & Sons, Inc.