Although African-Americans constitute only about 12.4% of the population of
the United States of America (USA), they comprise over 30% of the end-stag
e renal disease (ESRD) patient population. Diabetes mellitus (predominantly
type 2) is the most frequently reported cause of ESRD in all racial and et
hnic groups in the USA. However, hypertensive renal disease is reported as
the dominant cause of ESRD in African-Americans. In general, all racial and
ethnic minority group in the USA have greater incidence and prevalence rat
es of ESRD than Caucasians, However, survival probabilities in all ESRD pat
ients, dialysis patients, and cadaveric renal allograft recipients are grea
ter in African-Americans than in Caucasians. The suggested reasons for thes
e racial and ethnic disparities are discussed.