Hans J. Eysenck and Jeffrey A. Gray have proposed influential theories of t
he biological bases of personality traits. Eysenck's theory concerns the ex
traversion, neuroticism and psychoticism traits, whereas Gray proposes the
use of new, rotated axes of impulsivity and anxiety. Eysenck uses multiple
arousal systems as the central explanatory constructs, whereas Gray describ
es more specific systems related to behavioural inhibition and activation.
This article reviews the evidence relating to these theories provided by st
udies of c.n.s. and a.n.s. psychophysiology, subjective affect, conditionin
g and attention and performance. It discusses key predictive successes and
failures and methodological problems which may impede theory-testing. It is
concluded that there is a solid core of predictive support for the Eysenck
theory in some paradigms, such as the moderator effect of stimulation leve
l on individual differences in phasic electrodermal response and eyelid con
ditioning. In other settings, the theory fails to explain empirical data ad
equately, especially in studies of subjective response and attention and pe
rformance. Gray's theory has advanced research through stimulating interest
in moderation of personality effects by motivational variables. It also pr
ovides a better explanation than Eysenck's theory for certain data, such as
instrumental conditioning to reward stimuli and the positive affectivity o
f extraverts, Overall, however, Gray's theory explains a narrower range of
findings than Eysenck's. There is little evidence that Gray's revised perso
nality axes are generally more predictive of psychophysiological and perfor
mance criteria than Eysenck's original dimensions. Finally, it is suggested
that the assumptions of the biological approach to personality are in need
of reassessment. It is possible that the biological theories may be improv
ed through developments in methodology or through discriminating multiple s
ystems underpinning traits. For example, extraversion may have distinct "re
ticulo-cortical'' and "dopaminergic" aspects, Alternatively, the biological
approach may not in fact be adequate for explaining behavioural correlates
of traits. In this case, trait research should place more bases for person
ality. (C) 1999 Elsevier Science Ltd. All rights reserved.