Anticonvulsant hypersensitivity syndrome occurring as sepsis with multiorgan dysfunction

Authors
Citation
P. Marik, Anticonvulsant hypersensitivity syndrome occurring as sepsis with multiorgan dysfunction, PHARMACOTHE, 19(3), 1999, pp. 346-348
Citations number
22
Categorie Soggetti
Pharmacology
Journal title
PHARMACOTHERAPY
ISSN journal
02770008 → ACNP
Volume
19
Issue
3
Year of publication
1999
Pages
346 - 348
Database
ISI
SICI code
0277-0008(199903)19:3<346:AHSOAS>2.0.ZU;2-T
Abstract
Phenytoin is a highly effective and widely prescribed anticonvulsant agent. However, it is associated with both dose-related side effects and hypersen sitivity reactions. Life-threatening anticonvulsant hypersensitivity syndro me in one patient was characterized by a skin eruption and multisystem orga n dysfunction.