XRF ANALYSIS OF ARSENIC UPTAKING IN MICE ORGANS AND TISSUES

In this work, an investigation on the levels of uptaken arsenic in dif ferent organs and tissues of mice was carried out. Mice were given wat er, doped with 100 mu g/ml of As2O3, during a period of a week. The En ergy Dispersive X-Ray Fluorescence (EDXRF) technique was used for the measurements; the external standard (calibration curve) and the intern al standard (addition) methods were used to obtain concentrations. The se methods were used in order to minimize matrix effects (which in man y cases are complex and prone to errors) and to allow an easy calculat ion of As concentrations. The average concentrations obtained here wer e: 3.9 mu g/g for liver, 13 mu g/g for pre-stomach, 21 mu g/g for esop hagus, 2.9 mu g/ml for blood, and 42 mu g/ml for urine.