Acute immune thrombocytopenia in childhood. Are we treating the platelet count?

Authors
Citation
Ah. Sutor, Acute immune thrombocytopenia in childhood. Are we treating the platelet count?, SEM THROMB, 24(6), 1998, pp. 545-548
Citations number
42
Categorie Soggetti
Hematology,"Cardiovascular & Hematology Research
Journal title
SEMINARS IN THROMBOSIS AND HEMOSTASIS
ISSN journal
00946176 → ACNP
Volume
24
Issue
6
Year of publication
1998
Pages
545 - 548
Database
ISI
SICI code
0094-6176(1998)24:6<545:AITICA>2.0.ZU;2-6
Abstract
Acute immune thrombocytopenia (ITP) in children is a benign disease, presen ting mostly with skin purpura and minor bleeds. It has a high rate of spont aneous remission. Intracranial hemorrhage (ICH) is extremely rare; the risk is higher during the chronic phase and in children with additional risk fa ctors, The threshold platelet count in ITP is not known because of problems with platelet counting in thrombocytopenia and the lack of clinical data. The threshold is probably lower than in leukemia, because primary hemostasi s is better in ITP, So far, there is no proof for the clinical efficacy of treatment or prophylaxis with intravenous immunoglobulin (IVIg) and glucoco rticoids (GC), medications that have several adverse effects. The question remains open whether or not we are treating the platelet count in children with acute ITP.