M. Radosevich, Research and development commitments in an integrated plasma collection and plasma fractionation environment, SEM THROMB, 24(2), 1998, pp. 157-161
Plasma fractionation has emerged as one of the most scientifically demandin
g fields in the biopharmaceutical area. Producing safe plasma derivatives i
mplies the development, use, and proper understanding of sensitive testing
technologies to detect infection markers in starting plasma. It also requir
es the implementation of carefully selected, nondenaturing, efficient plasm
a protein purification and viral reduction technologies that do not alter t
he physiological functions and clinical potential of plasma proteins. Succe
ss in this field can be achieved only by a strong commitment to sustain con
stant research and development of projects targeting the production of safe
r and innovative plasma products.