H. Schilling et al., LONG-TERM RESULTS AFTER LOW-DOSE OCULAR IRRADIATION FOR CHOROIDAL HEMANGIOMAS, British journal of ophthalmology, 81(4), 1997, pp. 267-273
Aim/background-The most common choice of treatment for choroidal haema
ngiomas (CH) in the past has been the employment of scatter photocoagu
lation of the surface. This management often requires repetitive treat
ment or additional invasive management due to massive exudative detach
ment of the retina. The aim of this retrospective study was to investi
gate the outcome of the alternative application of low dose external b
eam irradiation with high energetic photons on these tumours. Methods-
A total absorbed dose of 20 Gy was applied to a total of 51 symptomati
c eyes: 36 with a circumscribed CH of the posterior pole and 15 with d
iffuse CH as part of the Sturge-Weber syndrome. The indication for tre
atment was an exudative retinal detachment including or threatening th
e fovea. The mean follow up times in each group were 4.5 and 5.3 years
, respectively. Out of a group of 33 patients from whom reliable data
could be derived, 17 had symptoms lasting longer than 6 months. Result
s-In 23 cases (63.8%) with circumscribed CH complete resolution of the
subretinal fluid was achieved; the remaining 13 cases (36.2%) showed
residual Germany serous detachment distant to the fovea. The visual ac
uity improved by two or more lines in 14 cases (38.9%), remained stabl
e in 14 cases (38.9%), and decreased in eight cases (22.2%). The funct
ional success was dependent on the lag duration between onset of first
subjective symptoms and treatment. The morphological results with dif
fuse CH were similar to those of the group of circumscribed CH. The vi
sual acuity (VA) at last examination was improved in seven cases (46.6
%); in the remaining eight cases, VA was unchanged or had deteriorated
. The poor functional outcome in the latter was mainly attributable to
secondary glaucoma. Conclusion-External beam irradiation is a useful
and a low invasive therapeutic option for CH. A successful functional
outcome is dependent on the time delay between first onset of symptoms
and the beginning of therapy, the formation of subretinal fibrosis, a
nd also on secondary glaucoma in the case of Sturge-Weber syndrome.