M. Wright et al., COMPARISON OF THE EFFICACY OF DICLOFENAC AND BETAMETHASONE FOLLOWING STRABISMUS SURGERY, British journal of ophthalmology, 81(4), 1997, pp. 299-301
Aims-To compare the relative antiinflammatory potency and safety of to
pical diclofenac-gentamicin with betamethasone-neomycin following stra
bismus surgery. Methods-A single centre, single observer, prospective,
randomised, and double masked clinical trial of 25 children undergoin
g bilateral symmetrical horizontal strabismus surgery was carried out.
One eye received diclofenac-gentamicin and the contralateral eye rece
ived betamethasone-neomycin; both treatments were instilled four times
a day for 4 weeks postoperatively. Ocular inflammation was assessed a
t 1 and 4 weeks postoperatively, objectively by comparison with a phot
ographic chart and subjectively by questionnaire. Results-There was no
statistically significant difference in the rate of resolution of the
inflammatory response between each group at both visits. Conclusion-D
iclofenac appears to be as effective as betamethasone in controlling p
ostoperative inflammation following strabismus surgery and may offer a
safer alternative to the use of topical steroids.