COMPARISON OF THE EFFICACY OF DICLOFENAC AND BETAMETHASONE FOLLOWING STRABISMUS SURGERY

Citation
M. Wright et al., COMPARISON OF THE EFFICACY OF DICLOFENAC AND BETAMETHASONE FOLLOWING STRABISMUS SURGERY, British journal of ophthalmology, 81(4), 1997, pp. 299-301
Citations number
14
Categorie Soggetti
Ophthalmology
ISSN journal
00071161
Volume
81
Issue
4
Year of publication
1997
Pages
299 - 301
Database
ISI
SICI code
0007-1161(1997)81:4<299:COTEOD>2.0.ZU;2-B
Abstract
Aims-To compare the relative antiinflammatory potency and safety of to pical diclofenac-gentamicin with betamethasone-neomycin following stra bismus surgery. Methods-A single centre, single observer, prospective, randomised, and double masked clinical trial of 25 children undergoin g bilateral symmetrical horizontal strabismus surgery was carried out. One eye received diclofenac-gentamicin and the contralateral eye rece ived betamethasone-neomycin; both treatments were instilled four times a day for 4 weeks postoperatively. Ocular inflammation was assessed a t 1 and 4 weeks postoperatively, objectively by comparison with a phot ographic chart and subjectively by questionnaire. Results-There was no statistically significant difference in the rate of resolution of the inflammatory response between each group at both visits. Conclusion-D iclofenac appears to be as effective as betamethasone in controlling p ostoperative inflammation following strabismus surgery and may offer a safer alternative to the use of topical steroids.