A novel Fremy's salt-mediated oxidation and rearrangement of anilines intoamino ortho-diketones. Applications to the synthesis of pyrrolobenzodiazepines
Ga. Kraus et N. Selvakumar, A novel Fremy's salt-mediated oxidation and rearrangement of anilines intoamino ortho-diketones. Applications to the synthesis of pyrrolobenzodiazepines, TETRAHEDR L, 40(11), 1999, pp. 2039-2040
The reaction of anilines 1, 3, and 5 with 4.4 equivalents of Fremy's salt a
ffords ortho-quinones in good yields via a one-pot five-step sequence. (C)
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