Tandem aldol-allylation reactions: Double C-C bond formation using silicon-tethered dinucleophiles

Authors
Frost, LM Smith, JD Berrisford, DJ
Citation
Lm. Frost et al., Tandem aldol-allylation reactions: Double C-C bond formation using silicon-tethered dinucleophiles, TETRAHEDR L, 40(11), 1999, pp. 2183-2186
Citations number
19
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
11
Year of publication
1999
Pages
2183 - 2186
Database
ISI
SICI code
0040-4039(19990312)40:11<2183:TARDCB>2.0.ZU;2-P
Abstract
A new tandem C-C bond forming process has been developed which utilises sil icon-tethered dinucleophiles and acetals under Lewis acid conditions. The r eaction incorporates a functionalised five carbon unit into both aromatic a nd aliphatic acetals, affording acyclic beta-alkoxyhomoallylic alcohols in good yields. (C) 1999 Elsevier Science Ltd. All rights reserved.