Lm. Frost et al., Tandem aldol-allylation reactions: Double C-C bond formation using silicon-tethered dinucleophiles, TETRAHEDR L, 40(11), 1999, pp. 2183-2186
A new tandem C-C bond forming process has been developed which utilises sil
icon-tethered dinucleophiles and acetals under Lewis acid conditions. The r
eaction incorporates a functionalised five carbon unit into both aromatic a
nd aliphatic acetals, affording acyclic beta-alkoxyhomoallylic alcohols in
good yields. (C) 1999 Elsevier Science Ltd. All rights reserved.