NPY Y1 RECEPTOR-LIKE IMMUNOREACTIVITY EXISTS IN A SUBPOPULATION OF BETA-ENDORPHIN IMMUNOREACTIVE NERVE-CELLS IN THE ARCUATE NUCLEUS - A DOUBLE IMMUNOLABELING ANALYSIS IN THE RAT
K. Fuxe et al., NPY Y1 RECEPTOR-LIKE IMMUNOREACTIVITY EXISTS IN A SUBPOPULATION OF BETA-ENDORPHIN IMMUNOREACTIVE NERVE-CELLS IN THE ARCUATE NUCLEUS - A DOUBLE IMMUNOLABELING ANALYSIS IN THE RAT, Neuroscience letters, 225(1), 1997, pp. 49-52
Double immunolabelling immunohistochemistry in the arcuate nucleus of
the rat demonstrates that neuropeptide Y (NPY) Y1 receptor like immuno
reactivity is strongly present in a subpopulation of beta-endorphin im
munoreactive nerve cell bodies, while the small NPY immunoreactive ner
ve cell bodies located medially lack NPY Y1 receptor like immunoreacti
vity. The NPY Y1 like immunoreactive nerve cell bodies lie in an arcua
te area rich in NPY immunoreactive nerve terminals forming an uniform
plexus. It is postulated that NPY Y1 receptors in beta-endorphin neuro
ns may mediate some actions of NPY on motivational processes and pain
control as well as on hypophyseal hormone secretion, involving at the
least in part a regulation of the tubero-infundibular DA neurons (C) 1
997 Elsevier Science Ireland Ltd.