NPY Y1 RECEPTOR-LIKE IMMUNOREACTIVITY EXISTS IN A SUBPOPULATION OF BETA-ENDORPHIN IMMUNOREACTIVE NERVE-CELLS IN THE ARCUATE NUCLEUS - A DOUBLE IMMUNOLABELING ANALYSIS IN THE RAT

Citation
K. Fuxe et al., NPY Y1 RECEPTOR-LIKE IMMUNOREACTIVITY EXISTS IN A SUBPOPULATION OF BETA-ENDORPHIN IMMUNOREACTIVE NERVE-CELLS IN THE ARCUATE NUCLEUS - A DOUBLE IMMUNOLABELING ANALYSIS IN THE RAT, Neuroscience letters, 225(1), 1997, pp. 49-52
Citations number
15
Categorie Soggetti
Neurosciences
Journal title
ISSN journal
03043940
Volume
225
Issue
1
Year of publication
1997
Pages
49 - 52
Database
ISI
SICI code
0304-3940(1997)225:1<49:NYRIEI>2.0.ZU;2-1
Abstract
Double immunolabelling immunohistochemistry in the arcuate nucleus of the rat demonstrates that neuropeptide Y (NPY) Y1 receptor like immuno reactivity is strongly present in a subpopulation of beta-endorphin im munoreactive nerve cell bodies, while the small NPY immunoreactive ner ve cell bodies located medially lack NPY Y1 receptor like immunoreacti vity. The NPY Y1 like immunoreactive nerve cell bodies lie in an arcua te area rich in NPY immunoreactive nerve terminals forming an uniform plexus. It is postulated that NPY Y1 receptors in beta-endorphin neuro ns may mediate some actions of NPY on motivational processes and pain control as well as on hypophyseal hormone secretion, involving at the least in part a regulation of the tubero-infundibular DA neurons (C) 1 997 Elsevier Science Ireland Ltd.