Effects of air pollution and smoking on chronic obstructive pulmonary disease and bronchial asthma

Citation
H. Sasaki et al., Effects of air pollution and smoking on chronic obstructive pulmonary disease and bronchial asthma, TOH J EX ME, 186(3), 1998, pp. 151-167
Citations number
73
Categorie Soggetti
Medical Research General Topics
Journal title
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
ISSN journal
00408727 → ACNP
Volume
186
Issue
3
Year of publication
1998
Pages
151 - 167
Database
ISI
SICI code
0040-8727(199811)186:3<151:EOAPAS>2.0.ZU;2-6
Abstract
Although both tobacco smoking and air pollution are believed to be environm ental factors affecting the prevalence of chronic obstructive pulmonary dis ease (COPD) and bronchial asthma, the mechanisms by which they induce/aggra vate these diseases are still not known in detail. While smoking has been d emonstrated to cause and aggravate COPD and bronchial asthma, the influence of air pollution, suspected to have hazardous environmental effects since the historical episodes of severe air pollution such as the London Smog, on the prevalence of airway diseases remains unclear. This is due, in part, t o changes over time in the nature of the air pollutants concerned. There ha ve been no consistent findings on the effects on airway diseases of air pol lutants at levels currently observed in developed countries. It is believed that cessation of smoking is the most important factor in preventing the d evelopment of COPD.