H. Sasaki et al., Effects of air pollution and smoking on chronic obstructive pulmonary disease and bronchial asthma, TOH J EX ME, 186(3), 1998, pp. 151-167
Although both tobacco smoking and air pollution are believed to be environm
ental factors affecting the prevalence of chronic obstructive pulmonary dis
ease (COPD) and bronchial asthma, the mechanisms by which they induce/aggra
vate these diseases are still not known in detail. While smoking has been d
emonstrated to cause and aggravate COPD and bronchial asthma, the influence
of air pollution, suspected to have hazardous environmental effects since
the historical episodes of severe air pollution such as the London Smog, on
the prevalence of airway diseases remains unclear. This is due, in part, t
o changes over time in the nature of the air pollutants concerned. There ha
ve been no consistent findings on the effects on airway diseases of air pol
lutants at levels currently observed in developed countries. It is believed
that cessation of smoking is the most important factor in preventing the d
evelopment of COPD.