Paracetamol 1 g given rectally at the end of minor gynaecological surgery is not efficacious in reducing postoperative pain

Citation
A. Hein et al., Paracetamol 1 g given rectally at the end of minor gynaecological surgery is not efficacious in reducing postoperative pain, ACT ANAE SC, 43(3), 1999, pp. 248-251
Citations number
18
Categorie Soggetti
Aneshtesia & Intensive Care","Medical Research Diagnosis & Treatment
Journal title
ACTA ANAESTHESIOLOGICA SCANDINAVICA
ISSN journal
00015172 → ACNP
Volume
43
Issue
3
Year of publication
1999
Pages
248 - 251
Database
ISI
SICI code
0001-5172(199903)43:3<248:P1GGRA>2.0.ZU;2-K
Abstract
Background: We studied the analgesic effects of 1 g paracetamol given recta lly at the end of surgery in a prospective, randomised, double-blind study. Methods: One hundred and forty ASA I-II women scheduled for elective termin ation of pregnancy under general anaesthesia were randomly allocated to rec eive paracetamol or placebo. All patients had standardised anaesthesia with propofol, fentanyl and oxygen in nitrous oxide. Postoperative pain was ass essed by VAS score. Results: We could find no difference regarding postoperative pain, need for analgesics or time to discharge between the groups. Conclusion: The routine use of 1 g paracetamol given rectally at the end of surgery after termination of pregnancy seems not to be justified.