A 1-alkylated pteridine, C15H19C6O3

Authors
Helliwell, M Dinsmore, A Garner, CD Joule, JA
Citation
M. Helliwell et al., A 1-alkylated pteridine, C15H19C6O3, ACT CRYST C, 55, 1999, pp. 254-256
Citations number
20
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
ISSN journal
01082701 → ACNP
Volume
55
Year of publication
1999
Part
2
Pages
254 - 256
Database
ISI
SICI code
0108-2701(19990215)55:<254:A1PC>2.0.ZU;2-5
Abstract
The crystal structure of 6-chloro-2-(N,N-dimethylaminomethyleneamino)-1-(pi valoyloxymethyl)pteridin-4-one confirms that the reaction of pterin 8-oxide with acetyl chloride in trifluoroacetic acid produces the 6-chloride, and that the minor product from alkylation of 6-chloro-2-(N,N-dimethylaminometh yleneamino)pteridin-4-one with chloromethyl pivaloate in dimethylformamide with potassium carbonate, is N-1-alkylated and not N-8- or C-4-O-alkylated.