Efficacy of methotrexate in the treatment of nonruptured ectopic pregnancy- A six year experience at Polish Mother's Memorial Institute

The use of methotrexate to treat ectopic pregnancy was introduced in the 19 90s. In 1982, Tanaka et al. was the first to treat intramural pregnancy with met hotrexate successfully (1). More recently, Ory et al. (2) and then Stovall et al. (3) used methotrexate to treat unruptured ectopic pregnancies. Stova ll et al. created the nonlaparoscopic diagnostic algorithm for ectopic preg nancy, which included serial assay of beta-hCG, progesterone levels, transv aginal ultrasound and curettage (4). In our six year study we qualified for conservative therapy 51 patients with unruptured ectopic pregnancy. We tre ated these patients with a single dose of methotrexate (50 mg/m(2)). Our re sults are compared to those of other authors who used similar diagnostic an d therapeutic techniques.