ENTERIC COATING OF HARD GELATIN CAPSULES .2. LIOAVAILABILITY OF FORMALDEHYDE-TREATED CAPSULES

Part 1 of this article defined the prerequisites which allow the gastr o-resistance stabilization of formaldehyde treated capsules. Part 2 ex amines the dissolution profiles of these capsules with different conte nts, This set of experiences allowed an evaluation of the quality, pot entialities and limitations of the developed coating process. The cont ents choice considered different solubilities because this is one of t he most important parameters that affect the release rate from capsule s. (C) 1997 Elsevier Science B.V.