RNA movies: visualizing RNA secondary structure spaces

Motivation: RNA Movies is a system for the visualization of RNA secondary s tructure spaces. Its input is a script consisting of primary and secondary structure information. From this script, the system fully automatically gen erates animated graphical structure representations. III this way it create s the impression of an RNA molecule exploring irs own two-dimensional struc ture space. Results: RNA Movies has been used to generate animations of a switching str ucture in the spliced leader RNA. of Leptomonas collosoma ann sequential fo ldings of potato spindle tuber viroid transcripts. Availability: Demonstrations of the animations mentioned in this paper can be I viewed on our Bioinformatics web server under the following address: h ttp://Bielefeld.DE/mamovies/. The RNA Movies software is available upon req uest from the authors. Contact: dirk@TechFak.Uni-Bielefeld.DE.