Bilateral basal ganglial necrosis after allogeneic bone marrow transplantation in a child with Kostmann syndrome

A 6-year-old girl underwent allogeneic BMT from a matched sibling donor for the treatment of Kostmann syndrome, She suddenly became drowsy on day 30 a fter BMT, and lost consciousness 2 days later, Cranial CT scan showed symme trical lesions suggesting bilateral necrosis in the basal ganglia. Clinical and laboratory investigations failed to reveal any evidence of neurometabo lic disease.