Purpose: To compare in vitro the contamination susceptibility of three need
leless and one standard needle injection systems, Methods: The Baxter inter
link, St. Paul
Medical Key-Lok, Braun SafSite, and Becton Dickinson heparin lock, were com
pared. Fifty of each were studied. Each system was connected to a culture b
ottle and injected 30 times over 72 hr. The manufacturers' directions were
followed except for Braun's,which rec ommend that a new sterile cap be used
after each injection. Instead, the same cap was used after each injection
to reflect day-to-day clinical practice. Culture bottles were subsequently
analyzed for bacterial growth.
Results: The contamination rates for the heparin lock, Interlink, Key-Lok,
and SafSite went 3/50 (6%), 6/50 (12%), 4/50 (8%), and 36/50 (72%), respect
ively All positive cultures grew coagulase-negative staphylococcus species.
There was no difference in contamination rates between the InterLink, Key-
Lok, and heparin lock designs. The contamination rate of the SafSite was hi
gher (P < 0.001) than the other three systems.
Conclusions: The Interlink and Key-Lok systems had a similarly low contamin
ation susceptibility as a standard needle injection system. It was not dear
if the high contamination rate found with the SafSite system was due to no
n-adherence to the manufacturer's directions for handling.