Citation
C. Ferreri et al., The thiyl radical-mediated isomerization of cis-monounsaturated fatty acidresidues in phospholipids: a novel path of membrane damage?, CHEM COMMUN, (5), 1999, pp. 407-408
Citations number
21
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345
→ ACNP
Issue
5
Year of publication
1999
Pages
407 - 408
Database
ISI
SICI code
1359-7345(19990307):5<407:TTRIOC>2.0.ZU;2-M
Abstract
Thiyl radicals, generated from biologically relevant thiols under biomimeti
c conditions, reversibly attack the double bonds of unsaturated phospholipi
ds containing cis-fatty acid residues either in lipid solutions or lipid ve
sicles, thus producing phospholipids containing trans-fatty acid residues i
n high yield.