Electrocatalytic oxidation and trace determination of catecholamine neurotransmitters at osmium complex polymer and Nafion dual-layer membrane carbon-base electrode

The fabrication and electrocatalytic characteristics of osmium complex poly mer [Os (bpy)(2)(PVP)(10)Cl]Cl(OsP) or OsP-Nafion dual-layer membrane modif ied carbon-base (glassy carbon or graphite) electrodes were studied, The el ectrocatalytic behaviour of these modified electrodes to the oxidation of c atecholamines(dopamine, epinephrine and norepinephrine) was investigated. T he kinetic parameters of these electrocatalytic reactions were obtained, Th e OsP-Nafion dual-layer membrane modified electrodes could eliminate effici ently the interference of ascorbic acid and could be used in quantitative d etermination of trace catecholamine levels, The modified elecrodes showed e xcellent sensibility, selectivity and stability.