Unlike other areas of rehabilitation, which typically follow a single incid
ent such as trauma or stroke and are followed by improvement (or at least a
n expectation of stable impairment), multiple sclerosis (MS) presents the p
roblem of progressive impairment and disability. In addition the nature and
course of this progression are variable, so that the population is heterog
eneous. Expectations for outcome must be modest, and measurement should be
focused on quality on life issues.
On a background of pre-existing complex disability, multiple single-case (b
efore and after) study designs often present the best evidence for effectiv
eness of the team approach and for specific interventions. This evidence is
presented and reviewed.