Human outer dense fiber gene, ODF2, localizes to chromosome 9q34

Authors
Shao, X Murthy, S Demetrick, DJ van der Hoorn, FA
Citation
X. Shao et al., Human outer dense fiber gene, ODF2, localizes to chromosome 9q34, CYTOG C GEN, 83(3-4), 1998, pp. 221-223
Citations number
18
Categorie Soggetti
Molecular Biology & Genetics
Journal title
CYTOGENETICS AND CELL GENETICS
ISSN journal
03010171 → ACNP
Volume
83
Issue
3-4
Year of publication
1998
Pages
221 - 223
Database
ISI
SICI code
0301-0171(1998)83:3-4<221:HODFGO>2.0.ZU;2-R
Abstract
We have isolated the human homolog of the rat Odf2 gene. In rat, Odf2, the 84-kDa major outer dense fiber protein, interacts strongly and specifically with Odf1, the 27kDa major outer dense fiber protein. The interaction is m ediated by leucine zippers during ODF assembly along the sperm axoneme. We compared homology and genomic structure to rat and mouse Odf2 genes. Using fluorescence in situ hybridization, we mapped the human Odf2 gene (ODF2) to chromosome 9q34.