The diagnosis of chronic pancreatitis in the UK largely rests on the combin
ation of the clinical presentation which usually features pain which is oft
en provoked by food and/ or alcohol. There is usually a 30 to 40-min delay
between the stimulus and the pain and, after exclusion of other causes of p
ain, an ERCP is performed. A minority of patients will have pancreatic func
tion tests carried out while increasingly the diagnosis is being made by MR
scanning. The control of pain is often the most important aspect of manage
ment to the patient. In those with large ducts due to compression of focal
areas of the duct system surgical by-pass therapy is indicated. There is a
bigger problem in patients with small ducts and chronic pancreatitis in who
m extensive resection may be inappropriate. Our experience with minimally i
nvasive thoracoscopic splanchnicectomy has been encouraging over the last t
hree years. Having previously tried both percutaneous coeliac ganglion bloc
k and surgical excision of this nerve tissue, it is a great deal easier to
carry out this procedure which usually takes only 15-20 min per side. Patie
nts are usually only admitted for 48 h and the immediate beneficial effect
usually results in opiate analgesia being discontinued with considerable im
provement in the quality of life. While there is a slight drop-off in benef
it between 6 and 12 months post-operatively, the clinical effectiveness of
this approach is to be commended and the author's experience will be presen
ted to support this view.