A mild method for the preparation of 8-substituted xanthines from 5,6-diaminouracils

Authors
de Araujo, AD Bacher, E Demnitz, FWJ Santos, DA
Citation
Ad. De Araujo et al., A mild method for the preparation of 8-substituted xanthines from 5,6-diaminouracils, HETEROCYCLE, 51(1), 1999, pp. 29-36
Citations number
22
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
51
Issue
1
Year of publication
1999
Pages
29 - 36
Database
ISI
SICI code
0385-5414(19990101)51:1<29:AMMFTP>2.0.ZU;2-B
Abstract
The Schiff base derivatives (3), prepared from the respective 5,6-diaminour acil (1) and aldehydes can be mildly oxidatively cyclized with (m) under ba r-CPBA in MeCN to afford C-8 substituted xanthines (6).