Stereoselective synthesis of enantiomerically pure isoxazolidine-fused delta-lactams

Authors
Chiacchio, U Corsaro, A Piperno, A
Citation
U. Chiacchio et al., Stereoselective synthesis of enantiomerically pure isoxazolidine-fused delta-lactams, HETEROCYCLE, 51(1), 1999, pp. 37-49
Citations number
17
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
51
Issue
1
Year of publication
1999
Pages
37 - 49
Database
ISI
SICI code
0385-5414(19990101)51:1<37:SSOEPI>2.0.ZU;2-0
Abstract
Enantiomerically pure isoxazolidine-fused delta-lactams have been obtained by intramolecular nitrone cycloaddition starting from homochiral amido alde hydes. The stereocenter of the homochiral precursor controls the stereochem ical course of the process.