A man with a swollen leg and abnormal globulins

A 72-year-old man presented with a two-week history of exertional dyspnea a nd nonclaudicatory pain and swelling in the right lower leg Elevating the l eg for short periods had not helped. The symptoms had begun soon after he t ook a nonsteroidal anti-inflammatory drug for right shoulder pain but persi sted after he stopped taking the drug. His history included two-pillow orth opnea, but that had not worsened in the last year. He had not experienced c hest discomfort.