Potentially carcinogenic cyclopenta[a]phenanthrenes. Part 12. Synthesis ofmetabolites of the carcinogen 16,17-dihydro-11-methoxy-15H-cyclopenta[a]phenanthrene
Mm. Coombs et Gw. Boyd, Potentially carcinogenic cyclopenta[a]phenanthrenes. Part 12. Synthesis ofmetabolites of the carcinogen 16,17-dihydro-11-methoxy-15H-cyclopenta[a]phenanthrene, J CHEM R-S, (11), 1998, pp. 692-693
Starting with 15,16-dihydro-11-methoxycyclopenta[a]phenanthren-17-one, the
isomeric 15- and 16-keto analogues have been synthesised along with all thr
ee isomeric secondary alcohols, the trans-16,17-diol and a number of other
derivatives, some of which are metabolites of the title compound.