Production of specific monoclonal antibodies to Aspergillus species and their use in immunohistochemical identification of aspergillosis

Authors
Fenelon, LE Hamilton, AJ Figueroa, JI Bartholomew, MA Allen, MH McCarthy, P Hay, RJ
Citation
Le. Fenelon et al., Production of specific monoclonal antibodies to Aspergillus species and their use in immunohistochemical identification of aspergillosis, J CLIN MICR, 37(4), 1999, pp. 1221-1223
Citations number
17
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
00951137 → ACNP
Volume
37
Issue
4
Year of publication
1999
Pages
1221 - 1223
Database
ISI
SICI code
0095-1137(199904)37:4<1221:POSMAT>2.0.ZU;2-M
Abstract
Two anti-Aspergillus murine monoclonal antibodies (MAbs), designated 164G a nd 611F, have been produced; both specifically recognize cytoplasmic antige ns of A. fumigatus, A. flavus, and A. niger by enzyme-linked immunosorbent assay. The MAbs can identify Aspergillus spp. both in frozen sections by im munofluorescence and in paraffin-embedded clinical specimens by immunofluor escence and immunoperoxidase staining.