Dg. Armstrong et al., SURGICAL MORBIDITY AND THE RISK OF AMPUTATION DUE TO INFECTED PUNCTURE WOUNDS IN DIABETIC VERSUS NONDIABETIC ADULTS, Southern medical journal, 90(4), 1997, pp. 384-389
We reviewed the hospital course of 77 diabetic and 69 nondiabetic subj
ects who had incision, drainage, and exploration of infected puncture
wounds of the foot. Diabetics were 5 times more likely to have multipl
e operations and 46 times more likely to have a lower extremity amputa
tion than nondiabetics. The interval from injury to surgery was signif
icantly longer in diabetics than nondiabetics. Total lymphocyte count
and hemoglobin, hematocrit, and albumin values were significantly lowe
r in diabetics than in nondiabetics. Diabetic amputees had higher prev
alences of nonpalpable pulses, nephropathy, neuropathy, and osteomyeli
tis as compared with diabetic nonamputees. The neuropathic diabetic fo
ot is not protected by pain. When combined with other comorbid factors
, this may increase morbidity associated with puncture wounds of the f
oot.