A 60 year-old woman with primary esophageal T-cell lymphoma in clinical sta
ge IEB is pre sented. Immunohistologic examination showed tumor cells to be
positive for anti-LCA, anti-UCHL-1, anti-MT-1, anti-CD3 antibodies, and ne
gative for anti-L26 antibody. Disappearance of dysphagia and improvement in
esophageal findings were noted after 65 Gy of irradiation, and biopsy spec
imens from the esophagus revealed no malignancy. Primary esophageal lymphom
a is extremely rare, and this T-cell lymphoma is only the fourth case repor
ted in the literature.