ATP-DEPENDENT PROTEASES THAT ALSO CHAPERONE PROTEIN BIOGENESIS

Authors
SUZUKI CK REP M VANDIJL JM SUDA K GRIVELL LA SCHATZ G
Citation
Ck. Suzuki et al., ATP-DEPENDENT PROTEASES THAT ALSO CHAPERONE PROTEIN BIOGENESIS, Trends in biochemical sciences, 22(4), 1997, pp. 118-123
Citations number
49
Categorie Soggetti
Biology
Journal title
Trends in biochemical sciences → ACNP
ISSN journal
09680004
Volume
22
Issue
4
Year of publication
1997
Pages
118 - 123
Database
ISI
SICI code
0968-0004(1997)22:4<118:APTACP>2.0.ZU;2-O
Abstract
The ATP-dependent proteases Clp and FtsH from bacteria, as well as mit ochondrial homologs of FtsH and Lon from yeast, may act as chaperones; they mediate not only proteolysis, but also the insertion of proteins into membranes and the disassembly or oligomerization of protein comp lexes. The coordination of such processes with selective proteolysis m ay function in the quality control of protein biogenesis.