Prenatal diagnosis of congenital varicella syndrome and detection of varicella-zoster virus in the fetus: A case report

Authors
Hartung, J Enders, G Chaoui, R Arents, A Tennstedt, C Bollmann, R
Citation
J. Hartung et al., Prenatal diagnosis of congenital varicella syndrome and detection of varicella-zoster virus in the fetus: A case report, PRENAT DIAG, 19(2), 1999, pp. 163-166
Citations number
4
Categorie Soggetti
Reproductive Medicine","Medical Research Diagnosis & Treatment
Journal title
PRENATAL DIAGNOSIS
ISSN journal
01973851 → ACNP
Volume
19
Issue
2
Year of publication
1999
Pages
163 - 166
Database
ISI
SICI code
0197-3851(199902)19:2<163:PDOCVS>2.0.ZU;2-O
Abstract
Varicella syndrome (VS) specific malformations were sonographically seen at 22 weeks and 3 days of gestation. Fetal infection was demonstrated by dete ction of varicella-zoster virus (VZV) DNA in fetal blood and amniotic fluid by polymerase chain reaction (PCR). Following therapeutic abortion, fetal infection was confirmed by detection of VZV DNA in several fetal tissues an d placenta, and by histopathological findings like miliary calcified necros es in fetal organs. Copyright (C) 1999 John Wiley & Sons, Ltd.