Although family history of alcoholism represents a major risk factor in the
development of drinking problems, the available empirical literature on th
is topic has raised significant questions regarding the strength and breadt
h of this relationship. In addition, few studies have evaluated factors tha
t can ameliorate or exacerbate risk for adverse outcomes among children of
alcoholics (COAs). The current study compared the drinking, psychiatric, an
d psychosocial status of 84 adult COAs with those of 111 offspring of norma
l controls and 102 offspring of psychiatric controls. Adult COAs were diffe
rentiated from control groups regarding alcohol and drug abuse and personal
ity characteristics associated with behavioral undercontrol. Furthermore, t
he drinking outcomes of female versus male offspring were most clearly diff
erentiated across groups. Future research directions are discussed.