Power spectrum analysis of heart rate variability (PSA of HRV) is a promisi
ng method, which can be used as an index of cardiac autonomic balance. PSA
of HRV is a noninvasive technique, based on ECG sampling of RR interval var
iation, thus providing a dynamic assessment of sympathetic and parasympathe
tic tone, reflecting the interactions between the two. It has been shown to
have potential value in various laboratory and clinical conditions. It is
influenced by many factors such as age, sex, position, breathing, smoking,
hour of the day and medications. Different methods of data processing by va
rious authors have often elicited conflicting results. Standard values are
not yet available to be used or compared in different settings. From the in
terest it has raised, it may be expected that this method will be in widesp
read use in clinical practice in the future, providing a useful toot, both
for diagnostic and prognostic purposes, as well as serving as a further aid
towards monitoring therapeutic interventions. This review highlights techn
iques of dynamic assessment of HRV and studies of its clinical applications
in psychiatry in particular. It raises the potentially important prognosti
c implications of protracted autonomic dysfunction in psychiatric patient p
opulations, especially for cardiovascular morbidity and mortality.