Synthesis of prelactone B

Authors
Hanefeld, U Hooper, AM Staunton, J
Citation
U. Hanefeld et al., Synthesis of prelactone B, SYNTHESIS-S, (3), 1999, pp. 401-403
Citations number
10
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
SYNTHESIS-STUTTGART
ISSN journal
00397881 → ACNP
Issue
3
Year of publication
1999
Pages
401 - 403
Database
ISI
SICI code
0039-7881(199903):3<401:SOPB>2.0.ZU;2-1
Abstract
Prelactone B (1a) and its isomer 1b are possible products of a truncated av ermectin polyketide synthase. In order to make them available as reference compounds they were synthesized in a six-step synthesis with 56% overall yi eld.