Lipase-mediated 'meso-tricks' to transform latently symmetrical D-aldoses into L-aldoses via alditols

Authors
Gamalevich, GD Morozov, BN Vlasyuk, AL Serebryakov, EP
Citation
Gd. Gamalevich et al., Lipase-mediated 'meso-tricks' to transform latently symmetrical D-aldoses into L-aldoses via alditols, TETRAHEDRON, 55(12), 1999, pp. 3665-3674
Citations number
35
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
55
Issue
12
Year of publication
1999
Pages
3665 - 3674
Database
ISI
SICI code
0040-4020(19990319)55:12<3665:L'TTLS>2.0.ZU;2-3
Abstract
L-Fucose and L-xylose were synthesized from dulcitol and xylitol, respectiv ely, using CCL- or PPL-mediated kinetic resolution as the key step. In the first case dissymmetrization was achieved directly by acylating a meso deri vative, while in the second it was preceded by the conversion of the meso p olyol into a racemic intermediate. (C) 1999 Elsevier Science Ltd. All right s reserved.