Citation
Jk. Fairweather et al., The role of hydrolases in a synthesis of some epoxyalkyl beta-C-cellobiosides, TETRAHEDRON, 55(12), 1999, pp. 3695-3706
Citations number
14
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020
→ ACNP
Volume
55
Issue
12
Year of publication
1999
Pages
3695 - 3706
Database
ISI
SICI code
0040-4020(19990319)55:12<3695:TROHIA>2.0.ZU;2-3
Abstract
An endoglucanase from Humicola insolens has been used to glycosylate a rang
e of alkenyl beta-D-C-glucopyranosides with beta-lactosyl fluoride. The res
ulting trisaccharides have been subjected to the action of a commercial bet
a-galactosidase to form alkenyl beta-C-cellobiosides. Oxidation of these ha
s given a range of epoxyalkyl beta-C-cellobiosides, putative inhibitors of
cellobiohydrolases. (C) 1999 Elsevier Science Ltd. All rights reserved.