Citation
Ft. Ferse et al., Acceptor site recognition of transglycosylase inhibitors - A beta-D-glucopyranosyl-(1 -> 2)-alpha-D-glucopyranuronamide-derived moenomycin analogue, TETRAHEDRON, 55(12), 1999, pp. 3749-3766
Citations number
36
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020
→ ACNP
Volume
55
Issue
12
Year of publication
1999
Pages
3749 - 3766
Database
ISI
SICI code
0040-4020(19990319)55:12<3749:ASROTI>2.0.ZU;2-7
Abstract
The synthesis, the antibiotic and the transglycosylase inibiting properties
of a disaccharide analogue of moenomycin A in which the NHAc group of unit
E is replaced by a hydroxyl function are described. It can be concluded th
at this NHAc group is essential for eliciting transglycosylase inhibiting p
roperties, in agreement with a recently established solution structure of m
oenomycin A. (C) 1999 Elsevier Science Ltd. All rights reserved.