(+)-Epoformin 1 and (-)-theobroxide 2 belong to a family of highly oxygenat
ed cyclohexane-based metabolites, mainly epoxides, that have been isolated
from bacteria, fungi, higher plants and molluscs.(1-5) These compounds have
stimulated several synthetic efforts(6-9) due to their biological activiti
es, which range from antifungal, antibacterial, antitumor, phytotoxic and e
nzyme inhibitory.(1-9).