2. Synthesis of the C.14-C.26 hydrophilic domain of amphidinolide B1 and formation of the (E)-1-1 ',3-trisubstituted diene sector

Authors
Eng, HM Myles, DC
Citation
Hm. Eng et Dc. Myles, 2. Synthesis of the C.14-C.26 hydrophilic domain of amphidinolide B1 and formation of the (E)-1-1 ',3-trisubstituted diene sector, TETRAHEDR L, 40(12), 1999, pp. 2279-2282
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
12
Year of publication
1999
Pages
2279 - 2282
Database
ISI
SICI code
0040-4039(19990319)40:12<2279:2SOTCH>2.0.ZU;2-I
Abstract
In the preceding letter, we described a synthesis of the conserved C.1-C.13 hydrophobic domain common to the potent B-type amphidinolides. In this let ter, we present syntheses of the C.14-C.26 hydrophilic domain specific to a mphidinolide B1 and a model for uniting the hydrophobic and hydrophilic dom ains to form the (E)-1,1',3-trisubstituted diene. (C) 1999 Published by Els evier Science Ltd. All rights reserved.