C. Bucher et al., First unequivocal synthesis of dissymmetrical trans N,N '-difunctionalized1,4,8,11-tetraazacyclotetradecane., TETRAHEDR L, 40(12), 1999, pp. 2315-2318
The first unequivocal synthesis of disymmetrical trans N,N-1-difunctionaliz
ed tetraazamacrocycles in cyclam series is reported. This convenient four-s
tep method can be used for the synthesis of various trans N,N-1-difunctiona
lized tetraazamacrocycles bearing two different pendant donor arms. (C) 199
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