Synthesis of alpha-fluoroalkyl substituted peptides via enzymatic fragmentcondensation

Authors
Bordusa, F Dahl, C Jakubke, HD Burger, K Koksch, B
Citation
F. Bordusa et al., Synthesis of alpha-fluoroalkyl substituted peptides via enzymatic fragmentcondensation, TETRAHEDR-A, 10(2), 1999, pp. 307-313
Citations number
33
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
2
Year of publication
1999
Pages
307 - 313
Database
ISI
SICI code
0957-4166(19990129)10:2<307:SOASPV>2.0.ZU;2-X
Abstract
A peptide library consisting of di- and tripeptide esters and tripeptide am ides, respectively, containing alpha-Tfm amino acids in different positions was synthesized and tested for enzymatic fragment condensations catalyzed by the proteases alpha-chymotrypsin, trypsin and clostripain. (C) 1999 Else vier Science Ltd. All rights reserved.