Ma. Gonzalez-martinez et al., On-line immunoanalysis for environmental pollutants: from batch assays to automated sensors, TRAC-TREND, 18(3), 1999, pp. 204-218
The development of antibody-based sensors has grown steadily during recent
years, and their use as routine instruments in pollution control programmes
might become reality in the 21st century. The conversion from batch immuno
assays to practical immunosensors has not been easy, owing to the sometimes
different principles employed in these methodologies, In this review we il
lustrate the main difficulties found in the development and implementation
of on-line immunosensors, as applied to the determination of organic pollut
ants such as pesticides. Some solutions to these problems are proposed, and
their validities discussed critically. (C) 1999 Elsevier Science B.V. All
rights reserved.