A new picornavirus isolated from bank voles (Clethrionomys glareolus)

Authors
Niklasson, B Kinnunen, L Hornfeldt, B Horling, J Benemar, C Hedlund, KO Matskova, L Hyypia, T Winberg, G
Citation
B. Niklasson et al., A new picornavirus isolated from bank voles (Clethrionomys glareolus), VIROLOGY, 255(1), 1999, pp. 86-93
Citations number
19
Categorie Soggetti
Microbiology
Journal title
VIROLOGY
ISSN journal
00426822 → ACNP
Volume
255
Issue
1
Year of publication
1999
Pages
86 - 93
Database
ISI
SICI code
0042-6822(19990301)255:1<86:ANPIFB>2.0.ZU;2-9
Abstract
A previously unknown picornavirus was isolated from bank votes (Clethrionom ys glareolus). Electron microscopy images and sequence data of the prototyp e isolate, named Ljungan virus, showed that it is a picornavirus. The amino acid sequences of predicted Ljungan virus capsid proteins VP2 and VP3 were closely related to the human pathogen echovirus 22 (approximately 70% simi larity). A partial 5' noncoding-region sequence of Ljungan virus showed the highest degree of relatedness to cardioviruses. Two additional isolates we re serologically and molecularly related to the prototype. (C) 1999 Academi c Press.