BACKGROUND: Two types of calcification have been observed in breast lesions
. The more common is composed mostly of calcium phosphate and is detected i
n routine histologic tissue sections of frequently malignant lesions, the r
are type is calcium oxalate and is found exclusively in benign cysts.
CASE: In a 47-year-old female, strongly birefringent polyhedral crystals of
calcium oxalate were detected in benign breast cyst fluid.
CONCLUSION: Calcium oxalate is not clearly visible on routine histologic se
ctions, and examination of the cytologic specimen under polarized light rev
eals them. Awareness of this potential pitfall might lead to conservative m
anagement.