Virtual endoscopy enables computer-generated 3-dimensional visualization of
a cavity by reconstructing 2-dimensional computed tomographic or magnetic
resonance data. The technique has been used experimentally to study the col
on, bronchi, ears, and other structures. Here, virtual laryngoscopies were
created from the cross-sectional image data of 3 patients. The cases repres
ented a normal airway, a squamous cell carcinoma of the glottic fold, and a
posterior glottic stenosis. These reconstructions included extraluminal an
atomy that is not typical of current virtual endoscopic techniques. The 2-d
imensional computed tomographic and magnetic resonance images of the patien
ts underwent post-processing for 3-dimensional reconstruction. The resultin
g models were imported into an experimental virtual endoscopy program for 1
) airway lumen generation and 2) interactive viewing. Though they could not
be used for biopsy, the virtual laryngoscopies provided, in a noninvasive
fashion, good simulation of endoscopy. Virtual endoscopy also gave the adde
d benefits of the ability to assess the transmural extent of disease and vi
ew the airway distal to areas of luminal compromise. This technology may we
ll provide clinical benefit in preoperative planning, staging, and intrapro
cedural guidance for head and neck disease and merits further study.