Citation
M. Lekka et al., Local elastic properties of cells studied by SFM, APPL SURF S, 141(3-4), 1999, pp. 345-349
Citations number
8
Categorie Soggetti
Apllied Physucs/Condensed Matter/Materiales Science","Material Science & Engineering
Journal title
APPLIED SURFACE SCIENCE
ISSN journal
01694332
→ ACNP
Volume
141
Issue
3-4
Year of publication
1999
Pages
345 - 349
Database
ISI
SICI code
0169-4332(199903)141:3-4<345:LEPOCS>2.0.ZU;2-5
Abstract
Scanning force microscopy (SFM) can be used in nano-indentation experiments
for very soft samples of elastic, organic materials. The present paper des
cribes the methodology of device calibration and Young's moduli determinati
on, to evaluate the elastic properties of living cells in their culture con
ditions. Two similar lines of normal cells (Hu609) and cancerous ones (T24)
were measured. A significant difference in Young's modulus for normal and
cancerous cells was detected. (C) 1999 Elsevier Science B.V. All rights res
erved.