We report mid-infrared observations of several luminous infrared galaxies (
LIGs) carried out with the Infrared Space Observatory. Our sample was chose
n to represent different phases of a merger sequence of galaxy-galaxy inter
action with special emphasis on early/intermediate stages of merging. The m
id-infrared emission of these LIGs shows extended structures for the early
and intermediate mergers, indicating that most of the mid-infrared luminosi
ties are not from a central active galactic nucleus. Both the infrared hard
ness (indicated by the IRAS 12, 25, and 60 mu m flux density ratios) and th
e peak-to-total Aux density ratios of these LIGs increase as projected sepa
ration of these interacting galaxies become smaller, consistent with increa
sing star formation activities that are concentrated to a smaller area as t
he merging process advances. These observations provide among the first obs
ervational constraint of largely theoretically based scenarios.